MOSCOW, Sept 4 - Russia�s �Sputnik V� COVID-19 vaccine, approved in the country last month, produced antibody response in all participants with no serious adverse events in small human trials, according to the first peer-reviewed results of the preventive published in The Lancet journal on Friday.
Results from early-phase non-randomised vaccine trials in a total of 76 people show that two formulations of the vaccine have a good safety profile detected over 42 days, and induce antibody responses in all participants within 21 days.
Secondary outcomes from the trial suggest the vaccine, approved last month by Russia, also produces a T cell response within 28 days, the researchers said.
The trials took place in two hospitals in Russia, and were open-label and non-randomised, meaning that participants knew that they were receiving the vaccine and were not assigned by chance to different treatment groups.
The trials involved healthy adults aged 18-60 years, who self-isolated as soon as they were registered, and remained in hospital for the first 28 days of the trial from when they were first vaccinated. � PTI
