2025 Nobel in Medicine goes to trio for discovering immune system’s ‘security guards’

Stockholm, Oct 6: Mary E Brunkow, Fred Ramsdell and Shimon Sakaguchi won the Nobel Prize in medicine on Monday for their discoveries concerning peripheral immune tolerance.

The award is the first of the 2025 Nobel Prize announcements and was announced by a panel at the Karolinska Institute in Stockholm.

Peripheral immune tolerance is one way the body helps keep the immune system from getting out of whack and attacking your own tissues instead of foreign invaders.

"The Nobel Prize laureates identified the immune system’s security guards, regulatory T cells, thus laying the foundation for a new field of research. The discoveries have also led to the development of potential medical treatments that are now being evaluated in clinical trials," read the official website of the coveted award.

Last year's prize was shared by Americans Victor Ambros and Gary Ruvkun for their discovery of microRNA, tiny bits of genetic material that serve as on and off switches inside cells that help control what the cells do and when they do it.

Nobel announcements continue with the physics prize on Tuesday, chemistry on Wednesday and literature on Thursday. The Nobel Peace Prize will be announced Friday and the Nobel Memorial Prize in economics October 13.

The award ceremony will be held December 10, the anniversary of the death of Alfred Nobel, who founded the prizes. Nobel was a wealthy Swedish industrialist and the inventor of dynamite. He died in 1896.

With inputs from PTI